Travaux académiques publiés

Emergence of the patient-actor in patient safety in France. A narrative review in social sciences and public health.
Mougeot F, Robelet M, Rambaud C, Occelli P, Buchet-Poyau K, Touzet S, Michel P.
Sante Publique. 2018 Jan Feb;30(1):73-81.
doi: 10.3917/spub.181.0073. Review.


L’expérience patient en chirurgie : du travail du patient à la sécurité des soins.
Mougeot F, Occelli P, Buchet-Poyau K, Robelet M, Touzet S, Michel P.
Risques et Qualité 2018 ; 15 : 77-83.


Development of the Persuasion Knowledge Scales of Sponsored Content (PKS-SC). (in press)
Boerman, S.C., Van Reijmersdal, E.A., Rozendaal, E., Dima, A.L.
International Journal of Advertising [2.451]

Sponsored content is now everywhere - advertisers place information about the products they are promoting in TV programmes, video games, blogs, with the purpose of persuading customers to buy these products. Do customers know they are being targeted by these persuasion efforts? Researchers from the Amsterdam School of Communication Research have developed a self-report tool that measures nine components of Persuasion Knowledge for this type of content. This paper presents the psychometric validation of this tool, performed in collaboration with Alex Dima, Marie Curie Fellow at HESPER. It measures several dimensions of persuasion knowledge, such as whether respondents are able to recognize SC, understand the advertiser's intention, recognize the source, the persuasive tactics, the economic model, reflect on its effectiveness, etc. The use of this scale in future research makes it possible to understand how this form of media literacy may influence decisions, including choices related to preventive health behaviours which are subject to commercial interests and influences.


Digital Technologies and Adherence in Respiratory Diseases: The Road Ahead.
Blakey, J.D., Bender, B., Dima, A.L., Weinman, J., Safiotti, G., Costello, R.W. (2018)

European Respiratory Journal
DOI: 10.1183/13993003.01147-2018 [10.569]

The recent development of digital technologies in respiratory care represent an opportunity to improve the quality of care, but this opportunity will only realize if several key prerequisites are met. In this paper, an interdisciplinary team of researchers and practitioners led by Dr. John Blakey, University of Liverpool, UK, review the potential and the necessary conditions for this to be achieved. This development needs to be accompanied by strong research evidence, a strong infrastructure and regulatory standards, involve patients and healthcare professionals thoughout the process, and plan for long-term integration in existing healthcare systems. The authors review these conditions in relation to current respiratory care and research.


Hospital Length of Stay Reduction Over Time and Patient Readmission for Severe Adverse Events Following Surgery.
Pascal L, Polazzi S, Piriou V, Cotte E, Wegrzyn J, Carty MJ, Chollet F, Sanchez S, Lifante JC, Duclos A.
Ann Surg. 2019 Jan 19. doi: 10.1097/SLA.0000000000003206. [Epub ahead of print] PubMed PMID:30676380.


Quel impact des programmes de prévention santé sur l’arbitrage autoprévention assurance?
J.Y. Lesueur,
Risques, les cahiers de l’assurance, 2018, N°114, pp.163-167.

Some recent institutional reforms in different countries introduced incentives to develop individual preventive care attitudes and a new health insurance market design where private insurers invests in preventive action. The case of the health french system is original because of its mixed private and public health insurance coverage system. In that way, the National Inter-Professional Agreement that was established since 2016 between insurance companies and private firms in France, generated new forms of private health insurance contrats that includes a free offer of preventive care services for policyholders. In this paper, Jean-Yves Lesueur evaluate the impact of this free health preventive services on the optimal policyholders decision between self-insurance (vs self-protection) and private market demand insurance. He demonstrates that the standard properties of insurance models in the line of Ehrlich and Becker (1972) call into question in these new institutional environment. Its results raised the debate on the optimal market design between the health profile of the insurant and its choice of health coverage.



  • Measurement of the potential geographic accessibility from call to definitive care for patient with acute stroke.
    Freyssenge J, Renard F, Schott AM, Derex L, Nighoghossian N, Tazarourte K, El Khoury C. 
    Int J Health Geogr. 2018.

There are new effective reperfusion therapies (thrombolysis and thrombectomie) in acute ischemic stroke which can be considered as secondary prevention treatment as they allow the diagnosis and management of stroke at early stage and thus lead to limitation of disability in case of ischemic stroke occurrence. These treatments are mostly delivered in Stroke Units and are only efficacious during a limited time window. Quick access to health services able of performing these reperfusion therapies is a key element. We have performed a simulation of geographical accessibility of these Stroke Units according to patients’ residence area to get estimation of accessibility of reperfusion therapies.


  • Improving Access to Thrombolysis and Inhospital Management Times in Ischemic Stroke: A Stepped-Wedge Randomized Trial.
    Haesebaert J, Nighoghossian N, Mercier C, Termoz A, Porthault S, Derex L, Gueugniaud P-Y, Bravant E, Rabilloud M, Schott A-M,
    Group*. Stroke. 2018

As a number of acute stroke patients do not recognize stroke symptoms and go to emergency services instead of calling 15, we have conducted a trial to experiment the efficacy of a training program for emergency nurses and practitioners based on simulation. We have demonstrated its efficacy to improve the number of patients having timely access to reperfusion therapy.


  • Secondary Prevention Three and Six Years after Stroke Using the French National Insurance Healthcare System Database.
    Mechtouff L, Haesebaert J, Viprey M, Tainturier V, Termoz A, Porthault-Chatard S, David JS, Derex L, Nighoghossian N, Schott AM
    Eur Neurol. 2018

After a first stroke, the risk of a recurrent stroke is increased. The importance of adherence to tertiary prevention medications is crucial to limit this risk. We have studied the adherence of stroke patients to their medication through the SNIIRAM databases. The study population consisted of 210 patients at 3 years and 163 patients at 6 years. Medication use at 3 and 6 years was, respectively, 80.9 and 79.8% for antithrombotics, 69.1 and 66.3% for antihypertensives, 60.5 and 55.2% for statins and 48.6 and 46.6% for optimal treatment defined as the treatment achieved by the use of the 3 drugs. Adherence to each class was good at 3 years and tended to decrease at 6 years. More than one patient out of 2 did not use the optimal preventive treatment.



About 4 to 10% of all cancers are linked to occupational exposure to harmful substances in developed countries, and in France, that 15,000 to 20,000 new cases of cancers each year have occupational causes. From a health and safety regulatory perspective, the French and European regulations prompt development of preventive and legislative measures. In this context, N. Havet and M. Plantier analyze the occupational exposures to carcinogenic, mutagenic and reprotoxic (CMR) agents in France, and the implementation of protection measures for these occupational exposures. The aim is to examine existing inequalities in exposure and protection, in order to better target prevention policies. Based on data from the French national cross-sectional survey of occupational hazards (2003, 2010), several aspects are explored:


  • Protections des travailleurs vis-à-vis des risques d’exposition aux agents cancérogènes, mutagènes et reprotoxiques (CMR) en France
    N. Havet, M. Plantier, A. Penot, B. Charbotel, M. Morelle, B. Fervers.
    Environnement, Risques and Santé, John Libbey Eurotext, 2018, 17 (1), pp. 40-47.

In the first study, they examine the disparities that exist in the implementation of protection measures to occupational exposures to CMR agents in France in 2010. Overall, the results show that protective measures still appear to be insufficient. The frequency of collective protections varied according to the CMR products, the characteristics of the employee characteristics, their job and of their company. Improving protective measures for skilled and unskilled workers seems a priority as collective protection measures are less frequent, despite higher prevalence, duration and intensity of exposure that they experience. Also, prevention efforts should be improved for workers with atypical schedules for whom the effectiveness of the implemented protective measures seems to be relatively limited.


  • Do regulations protect workers from occupational exposures to carcinogenic, mutagenic and reprotoxic (CMR) agents in France?
    N. Havet, A. Penot, M. Plantier, B. Charbotel, M. Morelle, B. Fervers.
    Occupational and Environmental Medicine, BMJ Publishing Group, 2018, 75 (5), pp.389 - 397.

In the second study, they explore the impact of regulations on the implementation of collective protections in France to occupational exposure to CMR agents in 2010. In particular, they investigate whether stricter regulations and longer exposures were associated with higher level of collective protection. The results suggest that the dissemination of evaluations of carcinogens by the International Agency for Research on Cancer (IARC) translate into improved protective measures even though the IARC classification has no mandatory impact on regulations.


  • Inequalities in the control of the occupational exposure in France to carcinogenic, mutagenic and reprotoxic chemicals
    N. Havet, A. Penot, M. Plantier, B. Charbotel, M. Morelle, B. Fervers. 
    European Journal of Public Health, Oxford University Press (OUP): Policy B - Oxford Open Option D, 2019, 29 (1), pp.140-147.

In the third study, they examine the availability of the various collective protections and personal protective equipment in 2010. Using multilevel logistic regressions, they highlight important discrepancies in exposure levels and protection measures as a function of the characteristics of employee’s job and their company. This study confirm that the main priority highlighted in the first study: the main priority in regard to prevention should be a focus on unskilled workers.


  • Trends in the control strategies for occupational exposure to carcinogenic, mutagenic, and reprotoxic chemicals in France (2003-2010)
    Havet, A. Penot, M. Plantier, B. Charbotel, M. Morelle , B. Fervers.
    Annals of Work Exposures and Health, 2019, in revision

Finally, in the fourth study they explore the trends for the various control measures that are available to employees exposed to CMRs, at two time points (2003 and 2010). At first, they show an important decrease of exposure situations without any protective measures between 2003 and 2010. However, the overall increase in exposure situations involving protective measures masks a number of differences in exposure between employee categories. For example, differences in protections available between full-time and part-time workers disappeared in the 7-year period, while those between executives/managers and other employees increased, as did the gaps between large and small companies.